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TECHNOLOGY
PHOSPHOLIPID BIOLOGICAL EXCIPIENT
SELF-ASSEMBLING NANO DELIVERY TECHNOLOGY
SELF-ASSEMBLING NANO DELIVERY TECHNOLOGY
DKD phospholipid is a new generation biological excipient extracted from egg yolk and developed using a proprietary solvent-free technology, without the use of organic solvents or synthetic surfactants such as Tween 80 or ethanol.
Unlike conventional chemical excipients that primarily function as inert carriers, DKD’s excipient possesses a biomimetic structure compatible with cellular membranes. This enables efficient delivery of active compounds while actively participating in tissue repair processes and the modulation of local inflammatory responses.
This technology is protected by a United States patent (US12171902B1) and has been successfully applied across multiple clinical contexts, particularly in complex conditions such as second- and third-degree burns, necrotic ulcers, mucosal injuries, neurological damage, and endocrine-related tissue disorders.
UNITED STATES PATENT
US12171902B1
This patent protects a biological phospholipid excipient extracted from egg yolk using a solvent-free process. The technology enables the formation of naturally self-assembled nano-structures capable of efficiently delivering active compounds in biological and pharmaceutical applications.
VIEW FULL PATENTMECHANISM OF ACTION
The DKD phospholipid excipient operates through an amphiphilic emulsification structure that mimics the phospholipid bilayer of cellular membranes, enabling both efficient delivery of active compounds and biological interaction with damaged tissues.
a Deep delivery of active compounds into damaged tissue
- Phospholipids form liposome or phytosome structures that encapsulate active compounds.
- Protects active molecules from degradation caused by heat, pH variations, and enzymatic activity.
- Enhances penetration across biological barriers and significantly improves bioavailability.
b Biological interaction with damaged cells
- Stimulates actin polymerization and membrane-associated proteins, supporting granulation tissue formation.
- Modulates immune response by shifting macrophage activity from M1 (pro-inflammatory phase) to M2 (regenerative phase).
- Stabilizes cellular membranes and reduces oxidative stress in injured tissues.
c Formation of a protective lipid barrier and maintenance of physiological moisture
- Creates a semi-permeable lipid layer that protects tissue from microbial invasion.
- Prevents transepidermal water loss.
- Reduces excessive fibrotic activity, helping to minimize scar formation.
