Pioneering
Product

PHOSPHOLIPID BIOLOGICAL EXCIPIENT
APPLICATION IN WOUND HEALING

PL PRO is the first formulation marking DKD’s successful application of its proprietary phospholipid biological excipient platform in clinical practice. Developed from a self-assembling nano-delivery technology, PL PRO introduces a new therapeutic approach for severe tissue injuries, particularly burns, ulcers, necrotic lesions, and chronic wounds, while supporting inflammation modulation and tissue regeneration.

US Patent Document

UNITED STATES PATENT

US12150919B2

This patent protects the formulation and mechanism of action of topical preparations (gel, oil, and liquid solutions) utilizing phospholipid excipients. The system enhances transmembrane delivery of active compounds, promotes actin polymerization, stabilizes membrane proteins, and supports scar-free tissue regeneration.

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Biological Components – Endogenous Regenerative Mechanism

  • Main active ingredient: Nanocurcumin – an ultra-fine curcumin form capable of deep penetration with strong anti-inflammatory properties.
  • Supported by: Lipase enzyme – activates localized biological reactions at the application site.
  • Excipient platform: Phospholipids extracted from egg yolk using a solvent-free technology – forming natural nanoliposomes that enhance bioavailability by up to 2,000-fold.

Unlike conventional products that only support superficial healing, PL PRO works deeper at the biological level:

  • Forms a protective lipid membrane over damaged tissue.
  • Stimulates actin polymerization and membrane proteins (villin-1), supporting tissue restructuring.
  • Helps prevent hypertrophic or atrophic scarring, preserving both aesthetic and functional outcomes.

Preclinical results and real-world user data have demonstrated

  • Healing of grade II–III burns within 7–10 days without the need for sedatives or corticosteroids.
  • Applied in compassionate treatment programs at central hospitals.
  • Non-irritating and suitable for children as well as sensitive areas such as the eyes and perineal region.
Hành trình chữa lành – DKD

RELATED STORIES

Rare Disease

RARE DISEASE

A journey accompanying the healing process of a premature infant diagnosed with a rare disease for which no effective treatment currently exists. This experience became a powerful motivation for us to continue researching rare diseases and developing innovative biological solutions.

Burn Injuries in Children

PEDIATRIC BURNS

No longer the traces of a burn injury – only healthy skin and a child’s smile remain. The child’s family agreed to share this story as a message of hope, so that more children may gain access to safe, gentle, and humane treatment approaches.

Chronic Wounds

CHRONIC WOUNDS

After 32 years in a wheelchair following an accident, a patient faced a high risk of leg amputation due to deep tissue necrosis. During the waiting period for surgery, our formulation helped significantly improve wound recovery, and the patient was eventually discharged without the need for amputation.

ALL STORIES
Our Core Technology

OUR CORE TECHNOLOGY

A proprietary phospholipid biological excipient capable of self-assembling into Nano Liposome/Phytosome structures, enhancing bioavailability and optimizing therapeutic efficacy without adverse effects.

Derivative Technologies

DERIVATIVE TECHNOLOGIES

Each derivative technology represents a practical solution tailored to specific disease groups and age categories—following the principles of non-invasive therapy, biological compatibility, and long-term safety.